Senior Research Scientist – on-DNA synthesis

We are seeking a driven Senior Research Scientist – on-DNA synthesis to our new lab at AstraZeneca in Gothenburg!

Do you have hands-on experience and knowledge of on-DNA chemistry? Are you interested to establish and develop new on-DNA chemistry and contribute to the delivery of DNA encoded libraries (DEL)? Join us at our DEL synthesis lab in a company where we are committed to lifelong learning, growth and development! Welcome to AstraZeneca in Gothenburg!

Purpose, Offer and Benefits

In this role, you have the opportunity to contribute to the DEL synthesis capabilities in our new lab at AstraZeneca and deliver on-DNA compounds as well as contribute to the validation of building blocks for the production of a proprietary compound collection based on DEL.

We are a global, science-led BioPharmaceutical business and our innovative medicines are used by millions of patients worldwide. With our ground-breaking pipeline comes a bright future , exciting opportunities and varied work. You will be valued. Not only for your unique contribution, skills and background, but because we recognize people are our greatest asset. Here we are dedicated to being a Great Place to Work.

Your Responsibilities

What you´ll do:

• design and synthesize on-DNA compounds while also contributing to the continuous improvement of the DEL synthesis platform by evaluating new cutting edge synthetic approaches for on-DNA chemistry. 
• play a key role in validating new building blocks, extending the implementation of synthesis automation and in contributing to the improvement of our building blocks database.
• troubleshoot laboratory-based problems and make a significant contribution to the delivery of the team. 
• maintain access to the best internal and external science and enhance business reputation internally and externally through peer-reviewed publications and oral/poster presentations

The Bigger Picture

Our spectacular campus in Gothenburg is one of AstraZeneca´s three strategic science centers. The site is home to over 2,500 employees, from over 50 different nationalities. Gothenburg includes the complete range of functions, and as such offers plenty of development opportunities for a wide range of professionals. The site itself is designed with collaboration in mind: from the Coffee Lab to the gym, we have built a series of environments where innovation can happen.

This position is a 1 year consulting assignment. You will be employed by TNG during this time.

Our Expectations

You´re a chemist with a track record of applying innovative chemistry solutions, with resulting impact in project delivery. You also have:

• Ph.D. in a relevant chemistry discipline, or a Master degree in chemistry with minimum 5 years´ experience in synthetic organic chemistry.
• Expertise in synthetic organic chemistry, retrosynthesis, compound route design, purification and analysis.
• Knowledge of basic molecular biology techniques e.g gel electrophoresis, DNA ligation, PCR.
• Advanced knowledge of modern chemical literature, chemical technologies and applying new ideas to project delivery.
• A track record of driving innovation in chemistry related sciences