Published 2025-01-28

Scientist in the Microphysiological Systems at AZ

Exciting opportunity to join AstraZeneca in Gothenburg as a Scientist in the Microphysiological Systems (MPS) Team.

We are currently seeking an experienced Scientist to join our Microphysiological Systems (MPS) Team at AstraZeneca in Gothenburg. In this role, you will be responsible for executing and contributing to the practical delivery of MPS studies, as well as supporting the development, characterization, and optimization of new models.

Purpose, Offer and Benefits

At AstraZeneca, we follow the science to explore and innovate. We are unlocking the power of what science can do, working towards treating, preventing, modifying and even curing some of the world´s most complex diseases. If you´re driven by curiosity and courage, inspired by the possibility of doing things that have never been done before, this is the place for you.

This is a one-year consultant assignment, expected to start on April 1st, with the possibility of an earlier start. You will be employed by TNG during the assignment period.

Your Responsibilities

You will execute and provide input into the practical delivery of MPS studies and support the development, characterization, and optimization of new models.

Responsibilities include:

• Take part in the design, conduct, interpretation and reporting of studies with advanced cell models and MPS.
• Carry out various downstream analyses from the cell culture samples with versatile in-vitro analytical methods such as, but not limited to, ELISA’s, qPCR, staining and imaging.
• Join further model development activities to support drug projects with MPS data for resolving mechanisms of action, target identification, and candidate drug evaluation.
• Effectively communicate and collaborate across the Early CVRM and with the key stakeholders in other functions.

The Bigger Picture

This role will be based in the MPS team at the Early Cardiovascular, Renal and Metabolism (CVRM) department in our dynamic R&D site in Gothenburg, Sweden. The MPS team establishes and applies state-of-the-art MPS platforms to support the CVRM portfolio with emerging therapeutic area needs and new drug modalities. Our mission is to improve translatability from in vitro models to humans and accelerate drug discovery and development.

Our Expectations

Essential for the role:

• Master’s degree + 2 years of relevant experience.
• Background in Pharmacy, Biology, Biotechnology, Biochemistry, Medical Biosciences, Bioengineering or similar
• Strong hands-on cell culture experience
• Experience with primary cells or hPSCs
• Versatile in-vitro analytical methods (e.g., qPCR, staining and high-content imaging, plate-based assays e.g., ELISAs)
• Independent study design, laboratory work, and data analysis
• Data visualization and statistical analysis
• Excellent interpersonal skills and excellent communication skills in English, both verbal and in writing
• Strong ability to engage and collaborate across boundaries with a problem-solving attitude and focus on delivery